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Jean-Yves Blay Selected Research

Giant Cell Tumor of Bone

1/2021Malignancy in giant cell tumor of bone: analysis of an open-label phase 2 study of denosumab.
1/2016Current status and unanswered questions on the use of Denosumab in giant cell tumor of bone.
9/2012Giant-cell tumor of bone, anti-RANKL therapy.
8/2012Denosumab induces tumor reduction and bone formation in patients with giant-cell tumor of bone.

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Jean-Yves Blay Research Topics

Disease

210Neoplasms (Cancer)
04/2024 - 06/2002
159Sarcoma (Soft Tissue Sarcoma)
02/2024 - 01/2003
60Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
01/2024 - 08/2004
33Disease Progression
01/2024 - 01/2006
25Neoplasm Metastasis (Metastasis)
08/2023 - 02/2007
20Leiomyosarcoma
07/2023 - 08/2006
20Breast Neoplasms (Breast Cancer)
12/2022 - 06/2004
20Neutropenia
01/2022 - 05/2006
19Osteosarcoma (Osteogenic Sarcoma)
11/2022 - 07/2005
18Hypertension (High Blood Pressure)
01/2022 - 07/2009
17Fatigue
01/2022 - 09/2006
14Liposarcoma
02/2024 - 01/2004
12Synovial Sarcoma (Synovioma)
03/2024 - 01/2004
11Hemangiosarcoma (Angiosarcoma)
05/2023 - 11/2008
11Nausea
01/2022 - 09/2006
10Thrombocytopenia (Thrombopenia)
12/2023 - 02/2008
9Ewing Sarcoma (Sarcoma, Ewing)
12/2023 - 10/2008
9Lymphopenia (Lymphocytopenia)
12/2021 - 12/2004
8Aggressive Fibromatosis (Desmoid)
01/2023 - 10/2008
7Myxoid Liposarcoma
03/2024 - 07/2007
7Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2024 - 12/2005
7Melanoma (Melanoma, Malignant)
01/2023 - 08/2010
7Brain Neoplasms (Brain Tumor)
01/2022 - 09/2005
7Febrile Neutropenia
11/2016 - 12/2004
6Infections
07/2023 - 05/2006
6COVID-19
03/2023 - 01/2021
6Giant Cell Tumors (Giant Cell Tumor)
03/2021 - 09/2012
6Colorectal Neoplasms (Colorectal Cancer)
06/2020 - 07/2007
6Lymphoma (Lymphomas)
01/2017 - 06/2004
5Carcinoma (Carcinomatosis)
01/2023 - 06/2004
4Rhabdomyosarcoma
12/2023 - 03/2006
4Pain (Aches)
12/2023 - 01/2017
4Asthenia
12/2023 - 08/2015
4Chordoma
10/2023 - 11/2016
4Multiple Myeloma
01/2023 - 11/2005
4Hyperthermia
10/2021 - 06/2010
4Giant Cell Tumor of Bone
01/2021 - 08/2012
4Weight Loss (Weight Reduction)
01/2020 - 05/2012
4Exanthema (Rash)
06/2014 - 09/2006

Drug/Important Bio-Agent (IBA)

69Imatinib Mesylate (Gleevec)FDA Link
04/2024 - 06/2002
32Tyrosine Kinase InhibitorsIBA
02/2023 - 03/2007
29TrabectedinIBA
01/2023 - 11/2005
28Doxorubicin (Adriamycin)FDA LinkGeneric
07/2023 - 11/2005
26Biomarkers (Surrogate Marker)IBA
02/2024 - 06/2004
21IfosfamideFDA LinkGeneric
03/2024 - 11/2005
21Sunitinib (Sutent)FDA Link
01/2024 - 03/2007
16regorafenibIBA
12/2023 - 01/2013
13Phosphotransferases (Kinase)IBA
12/2021 - 03/2007
11AnthracyclinesIBA
03/2024 - 07/2012
11Immune Checkpoint InhibitorsIBA
02/2024 - 01/2019
11pazopanibFDA Link
12/2020 - 07/2009
10CytokinesIBA
01/2022 - 12/2005
10DenosumabFDA Link
03/2021 - 08/2012
10Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2019 - 06/2004
9ripretinibIBA
01/2024 - 01/2020
9Proteins (Proteins, Gene)FDA Link
01/2022 - 07/2007
8RNA (Ribonucleic Acid)IBA
07/2023 - 07/2019
8Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
01/2021 - 08/2004
8VemurafenibIBA
01/2020 - 08/2015
8Cytotoxins (Cytolysins)IBA
06/2017 - 06/2004
7Sorafenib (BAY 43-9006)FDA Link
06/2023 - 01/2012
7DNA (Deoxyribonucleic Acid)IBA
12/2021 - 01/2007
7Paclitaxel (Taxol)FDA LinkGeneric
01/2021 - 03/2006
7Alanine Transaminase (SGPT)IBA
01/2020 - 10/2008
7Dacarbazine (DIC)FDA LinkGeneric
01/2020 - 10/2009
7Etoposide (VP 16)FDA LinkGeneric
01/2020 - 03/2006
6Messenger RNA (mRNA)IBA
03/2023 - 08/2011
6CrizotinibIBA
12/2021 - 01/2015
6LigandsIBA
01/2021 - 05/2011
6Docetaxel (Taxotere)FDA Link
01/2020 - 08/2006
6Interleukin-10 (Interleukin 10)IBA
03/2013 - 06/2004
6Interleukin-6 (Interleukin 6)IBA
08/2011 - 06/2004
5nilotinibFDA Link
12/2021 - 09/2009
5AntibodiesIBA
12/2021 - 07/2007
5GemcitabineFDA Link
01/2020 - 08/2006
5Monoclonal AntibodiesIBA
12/2017 - 11/2009
5MicroRNAs (MicroRNA)IBA
06/2015 - 01/2011
4ParaffinIBA
02/2024 - 05/2011
4VaccinesIBA
03/2023 - 01/2021
4Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2023 - 10/2014
4Angiogenesis InhibitorsIBA
10/2022 - 07/2007
4cabozantinibIBA
06/2022 - 01/2020
4Aspartate Aminotransferases (Aspartate Transaminase)IBA
01/2022 - 03/2015
4Transaminases (Aminotransferases)IBA
01/2020 - 06/2009
4Cisplatin (Platino)FDA LinkGeneric
01/2020 - 11/2008
4eribulinFDA Link
01/2019 - 10/2011
4Bevacizumab (Avastin)FDA Link
10/2018 - 07/2007
4Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
05/2010 - 08/2004
3pembrolizumabIBA
01/2024 - 01/2023

Therapy/Procedure

100Therapeutics
04/2024 - 02/2005
83Drug Therapy (Chemotherapy)
03/2024 - 01/2003
30Radiotherapy
02/2024 - 07/2005
14Neoadjuvant Therapy
02/2024 - 03/2006
14Immunotherapy
09/2023 - 03/2013
13Adjuvant Chemotherapy
01/2022 - 03/2006
8Precision Medicine
01/2022 - 06/2013
5Aftercare (After-Treatment)
12/2022 - 06/2013
4Combination Drug Therapy (Combination Chemotherapy)
01/2019 - 10/2011
4Intravenous Infusions
08/2016 - 01/2012
3Molecular Targeted Therapy
05/2023 - 01/2017